Biological Membranes

Biological Membranes and Membrane Schedule and Titles

Please click here for a pdf copy of the schedule

 

Sunday, June 19th, 2022: 5:00 pm -7:00 pm:  Informal Reception, The Drury

 

Monday, June 20th, 2022

 

8:45 am – 9:00 am:       Opening Remarks

 

9:00 am – 9:30 am:       Levental, Ilya

              Cell Membranes Sustain Phospholipid and Tension Imbalances via Cholesterol      Asymmetry   

 

9:30 am – 10:00 am:     Brown, Michael F.

              Femtosecond X-Ray Scattering and Protein Quakes of Visual Rhodopsin

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10:00 am – 10:30 am:   Grossfield, Alan

               Computing the Thermodynamics of Lipid Phase Separation using Molecular Simulations                                                 

 

10:30 am - 11:00 am:   Coffee Break

 

11:00 am – 11:30 am:   Budin, Itay

               Under Pressure: Membrane Biophysics at the Bottom of the Earth’s Oceans

 

11:30 am – 12:00 pm:   Brown, Frank

               Correlated Diffusion in Model Membranes

 

12:00 pm – 1:30 pm:    Lunch Break

 

1:30 pm – 2:00 pm:      Klauda, Jeffrey

             Nearing the Final Stage in the Ongoing Saga of Pairwise Additive and Polarizable Lipid Force Field Development in CHARMM

 

2:00 pm – 2:30 pm:      Lyman, Ed      

             Membrane Surface Viscosity from Equilibrium Simulations. Or, How I Burned a lot of  Cycles to Make a Table for Rich

 

2:30 pm – 3:00 pm:       Pastor, Rich

             Simulations of PIP2 Clustering: Specific Cation Effects and Calcium-Potassium Synergy

 

3:00 pm – 3:30 pm:      Coffee Break

 

3:30 pm – 4:00 pm:      Swanson, Jessica                                                                                                                                                                                              From Bilayers to Monolayers: Exploring the Physicochemical Control of Protein  Targeting to Lipid Droplets.

 

4:00 pm – 4:30 pm:      Nagle, John

              Double Double Toil and Trouble

 

4:30 pm – 5:00 pm:      Feigenson, Jerry                                                                                                                                                                                              Improving Our Picture of the Plasma Membrane: Rafts Induce Ordered Domains in a Simplified Model Cytoplasmic Leaflet

 

Tuesday, June 21st, 2022

 

12:30 pm – 1:00 pm:    Marrink, Siewert-Jan

                Perspective on Simulating Entire Cells

 

1:00 pm – 1:30 pm:      Bidone, Tamara                                                                                                                                                                                                Multiscale Modeling of Transmembrane Adhesion Receptors: from Molecular Dynamics Simulations to Mesoscale Approaches

 

1:30 pm – 2:00 pm:      Kim, Siyoung

             Seipin Nucleates Neutral Lipids and Grows Lipid Droplets

 

2:00 pm – 2:30 pm:      Cafiso, David

              The Target of Synaptotagmin 1 in Calcium-Regulated Synchronous Fusion:  Membranes or SNAREs?

 

2:30 pm – 3:00 pm:      Falke, Joe

              Regulation of Membrane-Bound Master Kinases in Lipid Signaling Pathways

 

3:00pm – 3:30pm:      Coffee Break

 

3:30 pm – 4:00 pm:      White, Steve

              Membrane Protein Assembly via SecA:  Insights into Translocon Thermodynamics

 

4:00 pm – 4:30 pm:      Tristram-Nagle, Stephanie

             Antimicrobial Peptide Mechanism Revealed with Scattering-guided MD Simulation

 

4:30 pm – 5:00 pm:      Gumbart, J. C.                                                                                                                                                                                                  Modeling the Bacterial Cell Envelope at Atomistic Resolution

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5:00 pm – 5:30 pm:      Ashkar, Rana

               Domain Induced Dynamics in Phase-Separating Lipid Membranes

 

Wednesday, June 22th, 2022

 

12:30 pm – 1:00 pm:    Kenworthy, Anne

                Molecular Architecture of the Building Blocks of Caveolae

 

1:00 pm – 1:30 pm:      Heberle, Fred

              Portrait of a Raft in vitro: Optimizing cryo-EM for Imaging Membrane Domains

 

1:30 pm – 2:00 pm:      Tamm, Lukas

             Role of Cholesterol in the Tug of War between Viral Fusion Proteins and Cellular Restriction Factors in Virus Entry

 

2:00 pm – 2:30 pm:      Kasson, Peter

              Protein-Lipid Interactions in Enveloped Virus Entry

                       

2:30 pm – 3:00 pm:      Voth, Greg

              Membrane Remodeling by Proteins via Multiscale Simulation

 

3:00 pm – 3:30 pm:      Coffee Break

 

3:30 pm – 4:00 pm:      Vanegas, Juan

              Unraveling the Mechanical Activation of the Bacterial MscL and the Angiotensin II Type 1 GPCR with MD Simulations

 

4:00 pm – 4:30 pm:      Rouse, Sarah L.

             Cardiolipin Signaling in Mitochondria

 

4:30 pm – 5:00 pm:      Lorent, Joseph

              Lipid Oxidation and Biophysical Membrane Properties

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5:00 pm – 5:30 pm:      Gnanakaran, Sandrasegaram (LANL)

              Membranes & Machine Learning: Optimizing the Transport of Signals and Drugs Across Membrane

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6:00 pm – 7:00 pm:       Happy Hour/Cash Bar

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7:00 pm – 9:00 pm:       Banquet Dinner

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Thursday, June 23rd, 2022

 

12:30 pm – 1:00 pm:    Tobias, Doug

                Regulation of Aquaporin-0 Water Permeability

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1:00 pm – 1:30 pm:      Kerr, Daniel

              A Holistic Mathematical Formalism for Determining Membrane Affinities of Peripheral Binding Proteins

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1:30 pm – 2:00 pm:      Stahelin, Rob

              Lipid-Dependent Assembly and Budding of Emerging Viral Pathogens

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2:00 pm – 2:30 pm:      Smith, Aurelia H.

               Sliding, Expanding, and Compressing: How Membranes Respond to Fluid Flow

 

2:30 pm – 3:00 pm:      Sodt, Alex

             Molecular Mechanisms of Material Softening in Complex Bilayers

 

3:00 pm – 3:30 pm:      Coffee Break

 

3:30 pm – 4:00 pm:      Monje-Galvan, Viviana

              Modeling Protein-Lipid Interactions in Mechanisms of Cell Death

 

4:00 pm – 4:30 pm:      Hristova, Kalina

             Direct Quantification of Ligand-induced Lipid and Protein Microdomains with Distinctive Signaling Properties

 

4:30 pm – 5:00 pm:      Ingolfsson, Helgi

              MuMMI, a Machine Learning-Driven Modeling Infrastructure for Coupling different Simulation Scales; showcased for RAS-RAF                      Membrane Interactions

 

5:00 pm – 5:30 pm:      Wimley, Bill

              Evolution and Optimization of pH-triggered Pore-Forming Peptides for Protein Delivery to Cells.